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난자 및 배아성숙이 시험관아기시술 성공률에 미치는 영향 / 이여일

14 재생산 기술 조회 수 199 추천 수 0 2016.12.16 09:30:52

nibp *.223.3.98 https://www.nibp.kr/xe/info4_3/78539

발행년 :	1997
구분 :	국내학술지
학술지명 :	Obstetrics & Gynecology Science
관련링크 :	http://www.riss.kr/link?id=A3360365

난자 및 배아성숙이 시험관아기시술 성공률에 미치는 영향
= The Impact of Oocyte Maturity and Embryo Quality on Pregnancy Rate of In Vitro fertilization-Embryo Transfer (IVF-ET) Program

저자명
이여일, 박현정, 김재훈
학술지명
Obstetrics & Gynecology Science
권호사항
Vol.40 No.5 [1997]
발행처
대한산부인과학회
발행처 URL
http://www.ksog.org
자료유형
학술저널
수록면
959-964(6쪽)
언어
Korean
발행년도
1997년
초록 (Abstract)
- There are a number of factors affecting the pregnancy rate in in vitro fertilization (IVF): the etiology of infertility, ages of husband and wife, the type of ovarian stimulation, the number of aspirated oocytes, the maturity of oocyte, embryo quality...
There are a number of factors affecting the pregnancy rate in in vitro fertilization (IVF): the etiology of infertility, ages of husband and wife, the type of ovarian stimulation, the number of aspirated oocytes, the maturity of oocyte, embryo quality, the number of fertilized oocytes, the cumulative embryo score, and the number of embryos transferred. Among them the maturity of oocyte and the quality of embryo appear to be the most important factors influencing the pregnancy rate. The aim of this study designed to evaluate the effect of oocyte maturity, embryo quality, the number of embryos transferred, and the cumulative embryo score to fertilization rate on whether the patient conceived or not. A total of 146 consecutive cycles of in vitro fertilization-embryo transfer(IVF-ET) were studied using two ovarian hyperstimulation protocols; follicular stimulating hormone(FSH)/ human menopausal gonadotropin(HMG)/human chorionic gonadotropin(hCG) and gonadotropin releasing hormone agonist(GnRH-a)/FSH/HMG/hCG.
Following were the results.
1. The quality and quantity of oocytes and embryos, fertilization rate, and cumulative embryo score between two ovarian hyperstimulation protocols were not different.
2. The more mature oocytes exhibited, the greater fertilization rates in both methods (p$lt;0.01).
3. The average numbers of embryos transferred were 3.65+-0.27 in conceived group and 2.54+-0.18 in nonconceived group, which was statistically higher in conceived group (p$lt;0.001).
4. The pregnancy rate was higher if any matured embryo(Grade I) was present among the embryos transferred(p$lt;0.05).
5. The average cumulative embryo score was 69.70+-6.13 inconceived group and 43.51 +-3.41 in nonconceived group, which was statistically higher in conceived group(p$lt;0.001).
These data suggest that the pregnancy rate is higher when the oocyte maturation is Better, the number of embryos transferred is greater, there is at least one matured embryo among the embryos transferred, and the cumulative embryo score is higher.