관련 논문 - 시험관 아기 시술에서 여성의 연령이 수정란의 질과 다태 임신 발생에 미치는 영향 / 이명섭

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시험관 아기 시술에서 여성의 연령이 수정란의 질과 다태 임신 발생에 미치는 영향 / 이명섭

14 재생산 기술 조회 수 181 추천 수 0 2016.12.16 10:22:55

nibp *.223.3.98 https://www.nibp.kr/xe/info4_3/78557

발행년 :	2000
구분 :	국내학술지
학술지명 :	Clinical and Experimental Reproductive Medicine
관련링크 :	http://www.riss.kr/link?id=A100664390

시험관 아기 시술에서 여성의 연령이 수정란의 질과 다태 임신 발생에 미치는 영향
= Influence of Maternal Age on Embryo Quality and the Frequency of Multiple Pregnancy in IVF-ET Program

저자명
이명섭, 박장옥, 정지학,박준숙, 강희규, 김동훈, 이호준
학술지명
Clinical and Experimental Reproductive Medicine
권호사항
Vol.27 No.3 [2000]
발행처
대한불임학회
발행처 URL
http://www.ksfs.or.kr/
자료유형
학술저널
수록면
261-265(5쪽)
언어
Korean
발행년도
2000년
초록 (Abstract)
- Objective: This study was performed to evaluate the influence of maternal age on embryo quality and the frequency of multiple pregnancy in IVF-ET program. Method: 86 conventional IVF-ET cycles were divided into three groups according to the age by 5 y...
Objective: This study was performed to evaluate the influence of maternal age on embryo quality and the frequency of multiple pregnancy in IVF-ET program. Method: 86 conventional IVF-ET cycles were divided into three groups according to the age by 5 year (group A: 26-30, group B: 31-35, group C: 36-40 yrs). The in vitro fertilization and development outcome (fertilization, cleavage and high quality embryo rate) and the pregnancy outcome (pregnancy, implantation, G-sac/high quality embryo and multiple pregnancy rate) were examined. And then, these results were compared among the groups. Results: The rates of fertilization (62.7, 68.5 and 65.4%, respectively) and cleavage (95.6, 97.6 and 98.0%, respectively) were not different among the groups. And the high quality embryo (HQE) rate also was not different among the groups (61.8, 62.9 and 62.8%, respectively). The pregnancy rate of group C (23.3%) was significantly lower than that of group A (41.2%) and B (48.7%). And the implantation rate was significantly decreased with advance in maternal age (group A; 17.3%, B; 12.6% and C; 6.0%). The G-sac/high quality embryo rate was significantly higher in group A (70.8%) when compared to group B (32.2%) and C (40.0%). On the other hand, the multiple pregnancy rate was significantly lower in group C (14.3%) when compared to group A (71.4%) and B (36.8%). Conclusion: The pregnancy rate was significantly decreased over 35 years. The G-sac/HQE and multiple pregnancy rate were significantly high below 31 years. Thus, these results suggest that the number of high quality embryo transferred should be limited by the age and another criteria for embryo quality evaluation were required for single embryo transfer.