인간 배아줄기세포의 동결에 이용되는 동결방지제에 대한 연구
= Recent Researches for Cryoprotectant Agents (CPAs) Used in Cryopreservation of Hhuman Embryonic Stem Cell

 
제어번호 99899109
저자명 정주원 ( Ju Won Jung )  ,오선경 ( Sun Kyung Oh )  ,최영민 ( Young Min Choi )
학술지명 人口醫學硏究論集
권호사항 Vol.26 No.- [2013] 
발행처 서울대학교 인구의학연구소 
자료유형 학술저널
수록면 18-24(7쪽)
언어 Korean
발행년도 2013년
판매처 한국학술정보

 
초록
Human embryonic stem cells (hESCs) are a great cell source for regenerative medicine including cell based therapy and drug development in clinical purposes. But hESCs could have low survival rates and reduced differentiation potential caused by high sensitivity during cryopreservation. Dimethyl sulfoxide (DMSO) is most commonly used as cryoprotectant agents for cell cryopreservation. Such cryoprotectant agents prevent cell damage during the freezing process and improve cell recovery after freezing-thawing. However, DMSO as a cryoprotectant is cytotoxic. In this review, we discussed cryoprectant agents and methods for effective cryopreservation of hESCs.

주제어
human embryonic stem cell  ,cryoprotectant agents  ,cryopreservation