유전자편집 작물의 개발 현황 및 농업생명공학기술의 국가 경쟁력 강화

= Strengthening the competitiveness of agricultural biotechnology through practical application of gene editing technology

• 저자[authors] 이신우 ( Shin-woo Lee )
• 학술지명[periodical name] 식물생명공학회지
• 권호사항[Volume/Issue] Vol.45No.3[2018]
• 발행처[publisher] 한국식물생명공학회(구 한국식물조직배양학회)
• 자료유형[Document Type] 학술저널
• 수록면[Pagination] 155-170
• 언어[language] Korean
• 발행년[Publication Year] 2018
• 주제어[descriptor] Gene Editing, SDN, Publications, Practical Application, Agricultural Biotechnology

다국어 초록[Multilingual Abstract] 

In this paper, mechanisms of gene editing technologies including ZFN, TALENS and CRISPR were briefly discussed with mutual advantages and disadvantages. Classification criteria of gene edited, site-directed mutagenesis (SDN) crops for regulatory purpose were also discussed. The number of studies using CRISPR technology was high and studies conducted on Arabidopsis thaliana and rice were highest, followed by tobacco, tomato, wheat, and corn. It has been applied to a variety of plants such as other grain crops, flower crops, vegetable crops, and fruit trees. The number of studies focused on practical application or commercialization in the future were also increasing yearly, and the scope of studies also expanded to include research on metabolic engineering for mass production of useful proteins or substances, development of disease resistant crops against viruses, bacteria, and fungi, abiotic environmental stressresistant crops, and increased yields. In addition to this, it was revealed that application range is becoming more diversified, including the development of parthenocarpic tomatoes, hybrid rice lines using male sterility and increased shattering resistance Brassica napus. It was also revealed that the number of CRISPR gene edited crops permitted by the USDA(APHIS) increases yearly, to be released in the international seed market soon.