원저 : 뇌사자 평가 중에 발생한 심장사 후 장기기증에 의한 신장이식: 단일기관 장기추적 결과
= Original Article: The Long-term Outcomes of Kidney Transplantation from Donation after Circulatory Death during Brain Death Donor Evaluation in a Single Center in Korea

제어번호 101730339
저자명 허나윤 ( Nayoon Hur )  , 박효준 ( Hyojun Park )  , 이교원 ( Kyowon Lee )  , 최규성 ( Gyuseong Choi )  ,

           김종만 ( Jong Man Kim )  , 박재범 ( Jae Berm Park )  , 권준혁 ( Choon Hyuck Kwon )  ,

           김성주 ( Sung Joo Kim )  ,   조재원 ( Jae-won Joh )  , 이석구 ( Suk-koo Lee ) 
학술지명 大韓移植學會誌(The Journal of the Korean Transplantation Society)
권호사항 Vol.29 No.4 [2015] 
발행처 대한이식학회 
발행처 URL http://www.ksot.org
자료유형 학술저널
수록면 216-227(12쪽)
언어 Korean
발행년도 2015년
등재정보 KCI등재후보
판매처 한국학술정보

 
초록
Background: While the number of deceased donor donations has increased in Korea, the organ shortage remains a major limitation for kidney transplantation. Donation after circulatory death (DCD) can be an option to expand the donor pool. In this study we evaluated the short and long term survival of grafts and patients and assessed the risk factors for graft failure. Methods: In a single center, from August 1997 to December 2013, 28 cases of recipients who received kidney transplantation from DCD were enrolled. Information about donor and recipient factors, graft conditions, and transplant outcomes was collected through review of medical records. We calculated overall graft and patient survival rates and the risk factors for graft failure according to donor criteria and whether or not delayed graft function (DGF) occurred. Results: There was no primary non-function, but DGF developed in 67.9% (19/28). Graft losses occurred in five patients during a median follow-up period of 68.2 months (4∼204). There was no significant difference in graft survival rates depending on the donor criteria and the occurrence of DGF. In addition, there were no noteworthy risk factors for graft failure among donor age, donor creatinine, extended criteria donor, recipient age, warm ischemic time, cold ischemic time, and DGF. Conclusions: In this study, despite the high incidence of DGF, the long-term graft and patient survival in kidney transplantation from DCD were acceptable. Therefore, DCD can be an alternative to expand the donor pool and to shorten the waiting time.

주제어
Kidney transplantation  , Donation after circulatory death  , Graft survival  , 신장이식  , 심장사 후 장기기증  , 이식편 생존율