종설 : 장기제공 전 뇌사자의 관리
= Review Article : Management and Evaluation Prior to Transplantation of Deceased Donor

 
제어번호 100033334
저자명 정종환 ( Jong Hwan Jung )  ,박성광 ( Sung Kwang Park )  ,이식 ( Sik Lee )
학술지명 大韓移植學會誌(The Journal of the Korean Transplantation Society)
권호사항 Vol.28 No.2 [2014] 
발행처 대한이식학회 
발행처URL http://www.ksot.org
자료유형 학술저널
수록면 51-58(8쪽)
언어 Korean
발행년도 2014년
등재정보 KCI등재후보
판매처 한국학술정보

 
초록
The number of people awaiting organ transplantation continues to exceed the number of organs available for transplantation, especially at a time when kidney transplantation is recognized as the best treatment option for end stage renal disease. There may be many reasons for this disparity of organ supply and demand, including the lack of consent, absence of an experienced coordinator team to help in closing the widening gap between organ supply and demand, and an unstandardized critical care management of potential organ donors. According to the report of the Korean Organ Transplant Registry in March 2014, due to a serious organ shortage in Korea, kidneys of deceased donors with low initial estimated glomerular filtration rate of ＜45 mL/min/1.73 m2 (21.2%) and expanded criteria donors (18.3%) are frequently used, and the number of wife donors and ABO-incompatible transplants for blood type O recipients is increasing. Because the number of donor organs compared with the demand is very restricted, proper management of deceased donors in the intensive care unit has been recognized as a critical determinant for a successful transplantation. Therefore, for successful transplantation of harvested organs, many medical doctors who play an integral role in the transplantation process should understand the pathophysiology of brain death-related systemic changes and well-designed management guidelines should be used prior to transplantation of deceased donors. This article reports on brain death-related systemic changes and proper management for preservation of function of donor organs.

주제어
장기이식  ,장기 보존  ,Organ transplantation  ,Organ preservation