유전성 암과 유전상담
= Hereditary cancer and genetic counseling

 
제어번호 82587098
저자명 정승용(Seung-Yong Jeong)
학술지명 대한의학유전학회지
권호사항 Vol.4 No.1 [2007] 
발행처 대한의학유전학회 
자료유형 학술저널
수록면 15-21(7쪽)
발행년도 2007년
KDC 517
등재정보 KCI등재
판매처 교보문고

 
초록
Hereditary syndromes cause approximately 5 to 10% of overall cancer cases. Cancer related with genetic syndromes are found elsewhere, including stomach, breast, colorectum, ovary, brain and so on. Because hereditary cancers are due to germline mutations, these patients have unique clinical features distinct from sporadic cancer. Generally these features include (ⅰ) early age-of onset of cancer, (ⅱ) frequent association with synchronous or metachronous tumors, (ⅲ) frequent bilateral involvement in paired organs (ⅳ) frequent association with other site tumors or characteristic clinical manifestation specific to each genetic syndrome. Due to these differences, the management strategy for patients with hereditary cancer is quite different from that for sporadic cancer. Additionally, there are important screening and surveillance implications for family members. Genetic counselling is prerequisite to these families for risk assessment by pedigree analysis, and guidance to clinical or genetic testing. The genes responsible for these syndromes has recently identified, as a result, genetic testing has become important determining factor in clinical decisions.

 
목차
서론
역사적 배경
유전성 종양 연구의 의의
유전성 종양의 특징 및 종류
유전성 종양의 원인 유전자
유전성종양 등록소
유전상담
참고문헌

주제어
Hereditary tumor  ,Hereditary cancer  ,Genetic counselling