유도만능줄기세포를 이용한 심장질환 관련 모델 구축에 관한 연구 동향
= Current Studies about Modeling of Cardiac Disorders Using Induced Pluripotent stem Cells

 
제어번호 100246017
저자명 김윤영 ( Yoon Young Kim )  ,구승엽 ( Seung Yup Ku )
학술지명 人口醫學硏究論集
권호사항 Vol.27 No.- [2014] 
발행처 서울대학교 인구의학연구소 
자료유형 학술저널
수록면 24-30(7쪽)
언어 Korean
발행년도 2014년
판매처 한국학술정보

 
초록
Induced pluripotent stem cells (iPSCs) are reprogrammed pluripotent-like cells holding great promise in regenerative medicine. There are numerous reports about the disease-specific derivation of iPSCs and analyses due to their almost embryonic stem cells-like abilities of self-renewing and differentiation into most of cell types. These features of iPSCs make them consider as a unique human cell model that is capable of replacing diverse animal models. In this review, we present an overview of the usage of iPSC-derived cardiomyocyte(iPSC-CM)as a human model of various heritable cardiac disorder.

주제어
Induced pluripotent stem dell  ,cardiac disorder  ,cardiomyocyte