인간 배아줄기세포와 인간 역분화줄기세포의 유전체 수준 비교
= Comparison of Human Embryonic Stem Cells and Human Induced Pluripotent Stem Cells Using Genome-wide Approach

  
 
제어번호 99899108
저자명 백진아 ( Jin Ah Baek )  ,최영민 ( Young Min Choi )
학술지명 人口醫學硏究論集
권호사항 Vol.26 No.- [2013] 
발행처 서울대학교 인구의학연구소 
자료유형 학술저널
수록면 11-17(7쪽)
언어 Korean
발행년도 2013년
판매처 한국학술정보

 
초록
Human pluripotent stem cells (hPSCs), which include human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), can self-renew while maintaining the pluripotency. They have been a prime candidate cell source for the development of cell replacement therapies and regenerative medicine. hESCs and hiPSCs are similar in morphology, cell-surface marker and teratoma formation capacity. However, questions remain on whether the epigenetic reprogramming is complete. For this reason, in this study, we compared the transcriptom and epigenetic properties between hESCs and hiPSCs.

주제어
hPSCs  ,hESCs  ,hiPSCs  ,transcriptome  ,epigenetic propertties