발행년 : | 2001 |
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구분 : | 국내학술지 |
학술지명 : | 영남의대학술지 Vol.18 No.1 |
관련링크 : | http://www.riss.kr/link?id=A3006739 |
간이식의 현재 = Current Status of Liver Transplantation
초록 (Abstract)
Liver transplantation is widely accepted as an effective therapeutic modality
for a variety of irreversible acute and chronic liver diseases for which no
satisfactory therapy is available. Following the first unsuccessful efforts at
human liver transplantation in 1963, development of the procedure evolved at
first slowly and steadily for 20 years and then rapidly over the past two
decades. The growth of liver transplantation was facilitated by the conclusion
of the national institutes of health consensus development conference in 1983
that liver transplantation is not an experimental procedure but an effective
therapy that deserves broader application. The number of liver transplantations
increased 2.4-fold(from 1,713 to 4,058) from 1988 to 1996, but the number of
patients on the UNOS(united network of organ sharing) liver list increased
12.1-fold(from 616 to 7,467) ; as would be expected, the number of deaths of
listed patients increased 4.9-fold(from 195 to 954). The current supply of donor
livers is insufficient to meet this need, and organ donation has been stagnant
or increased by only a few percent in recent years. These facts underscore the
importance of the appropriate selection of candidates for liver transplantation
and the development of operative procedures, such as living donor liver
transplant,
split liver transplant and auxiliary partial liver
transplant.
목차 (Table of Contents)
역사적 배경
간이식의 적응증과 수술시기
간이식의 절대적 금기
수혜자의 평가
사체 공여자의 평가
간이식 술식의 종류
생체 간이식의 장·단점
보조 간이식
면역 억제
수술 후 합병증
결과
우리나라의 간이식 현황
간이식의 세계적인 추세